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There are times you automatically reach for the aspirin, like when you have a mild headache. Sometimes, there is an interaction between the aspirin and other drugs you are taking - almost 1,200 drugs are known to interact with aspirin. But, in the case of xanax, there are no significant side effects if you take them both at the same time. This will be so even if there is a third drug being taken or you have been drinking grapefruit juice which affects the rate at which drugs are absorbed into your blood stream.
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